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Overview
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Pathways & interactions
Polysaccharide lyase family 8, C-terminal (IPR004103)
Short name: Lyase_8_C
Overlapping homologous superfamilies
- Polysaccharide lyase family 8-like, C-terminal (IPR011071)
Domain relationships
None.
Description
Proteins containing this domain consist of a group of secreted bacterial lyase enzymes capable of acting on hyaluronan (hyaluronate lyase, EC:4.2.2.1) and chondroitin (chondroitin AC lyase, EC:4.2.2.5) in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen [PMID: 14523022, PMID: 10329169]. This domain is almost always associated with the polysaccharide lyase family 8, N-terminal domain (see IPR003159). This entry represents the C-terminal domain of hyaluronate and chondroitin AC lyase enzymes.
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0016829 lyase activity
Cellular Component
GO:0005576 extracellular region
Contributing signatures
- PF02884 (Lyase_8_C)