Domain

Polysaccharide lyase family 8, C-terminal (IPR004103)

Short name: Lyase_8_C

Overlapping homologous superfamilies

Domain relationships

None.

Description

Proteins containing this domain consist of a group of secreted bacterial lyase enzymes capable of acting on hyaluronan (hyaluronate lyase, EC:4.2.2.1) and chondroitin (chondroitin AC lyase, EC:4.2.2.5) in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen [PMID: 14523022, PMID: 10329169]. This domain is almost always associated with the polysaccharide lyase family 8, N-terminal domain (see IPR003159). This entry represents the C-terminal domain of hyaluronate and chondroitin AC lyase enzymes.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016829 lyase activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam