Family

Nonstructural protein NS3/small envelope protein E (IPR003873)

Short name: NS3/E

Family relationships

None.

Description

This is a family of small nonstructural proteins, well conserved among Coronavirus strains. This protein is also found in Murine hepatitis virus as small envelope protein E. The human coronavirus EMC protein E acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport [PMID: 25733052].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam