tRNA wybutosine-synthesizing protein (IPR003827)

Short name: tRNA_yW-synthesising

Overlapping homologous superfamilies

Domain relationships



The methyltransferase TYW3 (tRNA-yW- synthesising protein 3) has been identified in yeast to be involved in wybutosine (yW) biosynthesis [PMID: 16642040]. yW is a complexly modified guanosine residue that contains a tricyclic base and is found at the 3'-position adjacent the anticodon of phenylalanine tRNA. TYW3 is an N-4 methylase that methylates yW-86 to yield yW-72 in an Ado-Met-dependent manner [PMID: 16642040].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.