Domain

Fe-S metabolism associated domain, SufE-like (IPR003808)

Short name: Fe-S_metab-assoc_dom

Domain relationships

None.

Description

This entry represents the core domain of SufE and related proteins. This domain of SufE shows strong structural similarity to IscU, and the sulfur-acceptor site in SufE coincides with the location of the cysteine residues mediating Fe-S cluster assembly in IscU. Thus, a conserved core structure is implicated in mediating the interactions of both SufE and IscU with the mutually homologous cysteine desulfurase enzymes present in their respective operons [PMID: 15522304].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam