ABC transporter substrate-binding protein PnrA-like (IPR003760)

Short name: PnrA-like

Overlapping homologous superfamilies


Domain relationships



Proteins containing this domain were originally annotated as basic membrane lipoproteins [PMID: 9350727]. However, several proteins containing this domain were later predicted as ABC transporter substrate-binding proteins, such as PnrA (also known as TmpC or TP0319) and RfuA (also known as Tpn38 or TP0298) from Treponema pallidum. PnrA transports purine nucleosides [PMID: 16418175], while RfuA transports riboflavin [PMID: 23404400]. Proteins containing this domain also include Med from Bacillus subtilis. Med was annotated as a transcriptional activator protein that regulates comK [PMID: 9335269]. This domain can also found at the N terminus of glutamate receptor-like proteins from Dictyostelium (slime mold) [PMID: 17501984].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005886 plasma membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.