Dihydroneopterin triphosphate diphosphatase (IPR003564)

Short name: DHNTPase

Overlapping homologous superfamilies

Family relationships



Dihydroneopterin triphosphate diphosphatase is a Nudix domain containing enzyme involved in folate biosynthesis. It catalyses the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate. It can also hydrolyse nucleoside triphosphates with a preference for dATP [PMID: 8798731, PMID: 17698004].

GO terms

Biological Process

GO:0046656 folic acid biosynthetic process

Molecular Function

GO:0008828 dATP pyrophosphohydrolase activity
GO:0019177 dihydroneopterin triphosphate pyrophosphohydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.