Family

Peptidase family S66 (IPR003507)

Short name: S66_fam

Overlapping homologous superfamilies

Family relationships

None.

Description

This entry includes proteins belonging to the MEROPS peptidase family S66, such as muramoyl-tetrapeptide carboxypeptidase and the microcin c7 self-immunity protein Q47511.

Muramoyl-tetrapeptide carboxypeptidase, also known as LD-carboxypeptidase A, hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. This activity has a role in murein recycling [PMID: 10428950, PMID: 18535144].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF
PANTHER