Family

Transcriptional regulator MraZ (IPR003444)

Short name: MraZ

Overlapping homologous superfamilies

Family relationships

None.

Description

This entry represents the MraZ protein from bacteria. This protein often is found with other genes of the dcw (division cell wall) gene cluster, including mraW, ftsI, murE, murF, ftsW, murG, etc. In E. coli, MraZ is a DNA-binding transcription factor [PMID: 24659771]. It acts as a repressor of Pmra, which is a promoter for mraZ and mraW. It also regulates the expression of genes outside the dcw cluster. Overproduction of Escherichia coli MraZ inhibits cell division [PMID: 24659771].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003700 DNA-binding transcription factor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
TIGRFAMs
PANTHER
HAMAP