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Overview
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Pathways & interactions
Transcriptional regulator MraZ (IPR003444)
Short name: MraZ
Overlapping homologous superfamilies
- SpoVT-AbrB domain superfamily (IPR037914)
- MraZ superfamily (IPR038619)
Family relationships
None.
Description
This entry represents the MraZ protein from bacteria. This protein often is found with other genes of the dcw (division cell wall) gene cluster, including mraW, ftsI, murE, murF, ftsW, murG, etc. In E. coli, MraZ is a DNA-binding transcription factor [PMID: 24659771]. It acts as a repressor of Pmra, which is a promoter for mraZ and mraW. It also regulates the expression of genes outside the dcw cluster. Overproduction of Escherichia coli MraZ inhibits cell division [PMID: 24659771].
GO terms
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Molecular Function
GO:0003700 DNA binding transcription factor activity
Cellular Component
No terms assigned in this category.