Beta propeller phytase (IPR003431)

Short name: BP_Phytase

Overlapping homologous superfamilies

Domain relationships



Phytase (EC: (phytate 3-phosphatase) is a secreted enzyme which hydrolyses phytate to release inorganic phosphate. According to their three-dimensional structures and catalytic mechanisms phytases are classified into different groups, one of them the beta propeller phytases [PMID: 11566134]. The beta-propeller phytase domain is made of six blades. Each blade is a highly curved sheet composed of four to five antiparallel beta-strands that are connected to each other in a topologically identical manner. The fourth strand of each blade is connected across the top of the molecule to the first strand of the next blade. The six blades are aligned along the shaft of the propeller, which is a distinct central channel filled with many well-bound water molecules. Between the blades, extensive hydrophobic interactions are observed [PMID: 10655618].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016158 3-phytase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles