Family

Histidine decarboxylase proenzyme (IPR003427)

Short name: His_de-COase_proenz

Family relationships

None.

Description

Histidine decarboxylase (EC:4.1.1.22) catalyses the formation of histamine from histidine [PMID: 11243783]. It requires a pyruvoyl group for its activity. Cleavage of the proenzyme PI chain yields two subunits, alpha and beta, which arrange as a hexamer (alpha beta) 6 by nonhydrolytic self-catalysis.

GO terms

Biological Process

GO:0006547 histidine metabolic process

Molecular Function

GO:0004398 histidine decarboxylase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
TIGRFAMs
PIRSF
ProDom
  • PD024462 (Pyruvoyl-dep_his_de-COase_PI)