Domain

SKI/SNO/DAC domain (IPR003380)

Short name: SKI/SNO/DAC

Domain relationships

None.

Description

This domain is about 100 amino acids long and contains a conserved CLPQ motif. The c-ski proto-oncogene has been shown to influence proliferation, morphological transformation and myogenic differentiation [PMID: 7999783]. Sno, a Ski proto-oncogene homologue, is expressed in two isoforms and plays a role in the response to proliferation stimuli. Dachshund also contains this domain. It is involved in various aspects of development [PMID: 7821215, PMID: 11290302].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam