Domain

Dishevelled protein domain (IPR003351)

Short name: Dishevelled_protein_dom

Domain relationships

None.

Description

This domain is specific to the signalling protein dishevelled. Dishevelled (Dsh/Dvl) is a highly conserved protein family that plays an important role in mediating Wnt signaling. Wnt signal transduction pathways control a variety of developmental and homeostatic events. Dishevelled is involved in both the canonical and non-canonical (B-catenin-independent) pathways [PMID: 20006983].

This domain is found adjacent to the PDZ domain (IPR001478), often in conjunction with DEP (IPR000591) and DIX (IPR001158).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam