AUX/IAA protein (IPR003311)

Short name: AUX_IAA

Overlapping homologous superfamilies


Family relationships



The Aux/IAA proteins are key regulators of auxin-modulated gene expression [PMID: 12036262]. The plant hormone auxin (indole-3-acetic acid, IAA) regulates diverse cellular and developmental responses in plants, including cell division, expansion, differentiation and patterning of embryo responses [PMID: 15061689]. Auxin can regulate the gene expression of several families, including GH3 and SAUR, as well as Aux/IAA itself. The Aux/IAA proteins act as repressors of auxin-induced gene expression, possibly through modulating the activity of DNA-binding auxin response factors (ARFs). Aux/IAA and ARF are thought to interact through C-terminal protein-protein interaction domains found in both Aux/IAA and ARF.

Recent evidence suggests that Aux/IAA proteins can also mediate light responses [PMID: 11544131]. Some members of the Aux/IAA family are longer and contain an N-terminal DNA binding domain [PMID: 9482737] and may have an early function in the establishment of vascular and body patterns in embryonic and post-embryonic development in some plants.

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.