Domain

Integrase, N-terminal zinc-binding domain (IPR003308)

Short name: Integrase_Zn-bd_dom_N

Domain relationships

Description

Retroviral integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains: an N-terminal zinc binding domain, a central catalytic core and a C-terminal DNA-binding domain [PMID: 11743009, PMID: 11101216]. Often found as part of the POL polyprotein.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles
SUPERFAMILY
Pfam