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Overview
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Pathways & interactions
Transcriptional coactivator p15 (PC4) (IPR003173)
Short name: PC4
Overlapping homologous superfamilies
None.
Domain relationships
None.
Description
This entry represents a domain found in p15 and other PC4 family members.
p15 has a bipartite structure composed of an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [PMID: 8062392]. The DNA-binding activity of the carboxy-terminal is disguised by the amino-terminal p15 domain. Activity is controlled by protein kinases that target the regulatory domain.
GO terms
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Molecular Function
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
Cellular Component
No terms assigned in this category.
Contributing signatures
- PF02229 (PC4)