Domain

Transcriptional coactivator p15 (PC4) (IPR003173)

Short name: PC4

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents a domain found in p15 and other PC4 family members.

p15 has a bipartite structure composed of an amino-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [PMID: 8062392]. The DNA-binding activity of the carboxy-terminal is disguised by the amino-terminal p15 domain. Activity is controlled by protein kinases that target the regulatory domain.

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding
GO:0003713 transcription coactivator activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam