Domain

Dynamin GTPase effector (IPR003130)

Short name: GED

Domain relationships

Description

Dynamin GTPase effector domain found in proteins related to dynamin.

Dynamin is a GTP-hydrolysing protein that is an essential participant in clathrin-mediated endocytosis by cells. It self-assembles into 'collars' in vivo at the necks of invaginated coated pits; the self-assembly of dynamin being coordinated by the GTPase domain. Mutation studies indicate that dynamin functions as a molecular regulator of receptor-mediated endocytosis [PMID: 10206643].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005525 GTP binding
GO:0003924 GTPase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam