Repeat

Phosphorylated immunoreceptor signalling ITAM (IPR003110)

Short name: Phos_immunorcpt_sig_ITAM

Description

Phosphorylated immunoreceptor signalling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases [PMID: 7594458]. Motif may be dually phosphorylated on tyrosine that links antigen receptors to downstream signalling machinery.

GO terms

Biological Process

GO:0007166 cell surface receptor signaling pathway

Molecular Function

GO:0004888 transmembrane signaling receptor activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
PROSITE profiles
Pfam