IPT domain (IPR002909)

Short name: IPT_dom

Overlapping homologous superfamilies

Domain relationships


The IPT (Ig-like, plexins, transcription factors) domain has an immunoglobulin like fold [PMID: 10390613]. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. The Ron tyrosine kinase receptor shares with the members of its subfamily (Met and Sea) a unique functional feature: the control of cell dissociation, motility, and invasion of extracellular matrices (scattering) [PMID: 8816464].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.