This archaeal enzyme family is involved in formation of methane from
carbon dioxide EC:22.214.171.124. The enzyme requires coenzyme F420 [PMID: 7852356].
Mukhopadhyay B, Purwantini E, Pihl TD, Reeve JN, Daniels L.
Cloning, sequencing, and transcriptional analysis of the coenzyme F420-dependent methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase gene from Methanobacterium thermoautotrophicum strain Marburg and functional expression in Escherichia coli. J. Biol. Chem. 270 2827-32 1995