Nascent polypeptide-associated complex NAC domain (IPR002715)

Short name: Nas_poly-pep-assoc_cplx_dom

Domain relationships



Nascent polypeptide-associated complex (NAC) is among the first ribosome-associated entities to bind the nascent polypeptide after peptide bond formation. The nascent polypeptide-associated complex (NAC) of yeast functions in the targeting process of ribosomes to the ER membrane [PMID: 10518932]. NAC may prevent binding of ribosome nascent chains (RNCs) without a signal sequence to yeast membranes.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles