Family

GTP cyclohydrolase 1 type 2/Nif3 (IPR002678)

Short name: GTP_cyclohydrolase_I/Nif3

Family relationships

Description

This family includes GTP cyclohydrolase 1 type 2 proteins from bacteria and Nif3 from budding yeasts.

In Helicobacter pylori, GTP cyclohydrolase 1 type 2 converts GTP to dihydroneopterin triphosphate [PMID: 23825549].

Nif3 interacts with the yeast transcriptional coactivator Ngg1p which is part of the ADA complex, the exact function of this interaction is unknown [PMID: 11124544, PMID: 8663102].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER
TIGRFAMs