Polyomavirus agnoprotein (IPR002643)

Short name: Polyoma_agno

Overlapping homologous superfamilies


Family relationships



This family consists of the DNA-binding protein or agnoprotein from various polyomaviruses. This protein is highly basic and can bind single stranded and double stranded DNA [PMID: 6262654]. Mutations in the agnoprotein produce smaller viral plaques, hence its function is not essential for growth in tissue culture cells but something has slowed in the normal replication cycle [PMID: 3027418]. There is also evidence suggesting that the agnogene and agnoprotein act as regulators of structural protein synthesis [PMID: 3027418].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003677 DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.