Domain

Aminoglycoside phosphotransferase (IPR002575)

Short name: Aminoglycoside_PTrfase

Domain relationships

Description

This entry consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include:- aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation [PMID: 2167474]. The proteins are found in a range of taxonomic groups.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam