Domain

Myogenic basic muscle-specific protein (IPR002546)

Short name: Basic

Domain relationships

None.

Description

This basic domain is found in the MyoD family of muscle specific proteins that control muscle development. The bHLH region of the MyoD family includes the basic domain and the Helix-loop-helix (HLH) motif. The bHLH region mediates specific DNA binding [PMID: 9343420]. With 12 residues of the basic domain involved in DNA binding [PMID: 8790335]. The basic domain forms an extended alpha helix in the structure.

GO terms

Biological Process

GO:0007517 muscle organ development
GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003677 DNA binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART