Cytochrome c assembly protein (IPR002541)

Short name: Cyt_c_assembly

Overlapping homologous superfamilies


Domain relationships



This domain is found in various proteins involved in cytochrome c assembly from mitochondria, chloroplast and bacteria; including among others CycK from Rhizobium leguminosarum [PMID: 7665469], CcmC and CcmF from Escherichia coli [PMID: 7635817], CcsA from Chlamydomonas [PMID: 8617725], and orf240 from Triticum aestivum (wheat) mitochondria [PMID: 7529870].

CcmC interacts directly with heme, and it is the only protein of the ccm operon that is strictly required for heme transfer [PMID: 10339610]. CcmF contains a b-type heme and is thought to be a cytochrome c synthetase [PMID: 22066495]. CcsA is required during biogenesis of c-type cytochromes at the step of heme attachment [PMID: 8617725]. R. leguminosarum CycK and wheat orf240 also contain a putative heme-binding motif [PMID: 7665469, PMID: 7529870].

GO terms

Biological Process

GO:0017004 cytochrome complex assembly

Molecular Function

GO:0020037 heme binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.