Domain

Picornavirus 2B protein (IPR002527)

Short name: Pico_P2B

Domain relationships

None.

Description

Poliovirus infection leads to drastic alterations in membrane permeability late during infection. Proteins 2B and 2BC enhance membrane permeability [PMID: 9218794, PMID: 8798506].

GO terms

Biological Process

GO:0018144 RNA-protein covalent cross-linking

Molecular Function

GO:0003968 RNA-directed RNA polymerase activity
GO:0008234 cysteine-type peptidase activity
GO:0016787 hydrolase activity
GO:0000166 nucleotide binding
GO:0016779 nucleotidyltransferase activity
GO:0008233 peptidase activity
GO:0005198 structural molecule activity
GO:0016740 transferase activity

Cellular Component

GO:0019012 virion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom