Cation efflux protein (IPR002524)

Short name: Cation_efflux

Overlapping homologous superfamilies

Family relationships


Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are considered to be efflux pumps that remove these ions from cells [PMID: 9696746, PMID: 8829543], however others are implicated in ion uptake [PMID: 1508175]. The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts, often containing low-complexity sequence.

GO terms

Biological Process

GO:0006812 cation transport
GO:0055085 transmembrane transport

Molecular Function

GO:0008324 cation transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.