Domain

Phosphoribosyl-AMP cyclohydrolase domain (IPR002496)

Short name: PRib_AMP_CycHydrolase_dom

Domain relationships

None.

Description

Phosphoribosyl-AMP cyclohydrolase EC:3.5.4.19 catalyses the third step in the histidine biosynthetic pathway: 5-phosphoribosyl-AMP + H2O = 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phospho-ribosyl) imidazole-4-carboxamide It requires Zn2+ ions for activity [PMID: 9931020].

GO terms

Biological Process

GO:0000105 histidine biosynthetic process

Molecular Function

GO:0004635 phosphoribosyl-AMP cyclohydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom