Family

Ornatin (IPR002463)

Short name: Ornatin

Family relationships

None.

Description

Ornatin is a potent glycoprotein IIb-IIIa (GP IIb-IIIa) antagonist and platelet aggregation inhibitor [PMID: 1765068]. The protein is 41-52 residues in length and contains the RGD recognition motif common in adhesion proteins, and 6 conserved cysteine residues. The sequences of ornatin isoforms B, C, D and E are highly similar, while isoforms A2 and A3 are less similar, lacking the N-terminal 9 residues. Ornatins share ~40% identity with decorsin, a GP IIb-IIIa antagonist isolated from the leech (Macrobdella decora) [PMID: 1765068].

GO terms

Biological Process

GO:0007155 cell adhesion
GO:0030193 regulation of blood coagulation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
PRINTS
Pfam