Natriuretic peptide, C type (IPR002406)

Short name: C_natriurtcpep

Family relationships


Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control of cardiovascular homeostatis, and sodium and water balance in general [PMID: 1652921, PMID: 2536732]. There are different NPs that vary in length but share a common core. All are processed from a single precursor. A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The family of NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these are brain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP) [PMID: 1828035]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) [PMID: 1352773]

C-type natriuretic peptide has vasorelaxant and cGMP-stimulating activities.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005179 hormone activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.