Family

Natriuretic peptide, C type (IPR002406)

Short name: C_natriurtcpep

Overlapping homologous superfamilies

None.

Family relationships

Description

Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control of cardiovascular homeostatis, and sodium and water balance in general [PMID: 1652921, PMID: 2536732]. There are different NPs that vary in length but share a common core. All are processed from a single precursor. A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The family of NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these are brain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP) [PMID: 1828035]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) [PMID: 1352773]

C-type natriuretic peptide has vasorelaxant and cGMP-stimulating activities.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005179 hormone activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS