3-beta hydroxysteroid dehydrogenase/isomerase (IPR002225)

Short name: 3Beta_OHSteriod_DH/Estase

Overlapping homologous superfamilies

Domain relationships


The enzyme 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase (3 beta-HSD) catalyses the oxidation and isomerisation of 5-ene-3 beta-hydroxypregnene and 5-ene-hydroxyandrostene steroid precursors into the corresponding 4-ene-ketosteroids necessary for the formation of all classes of steroid hormones.

GO terms

Biological Process

GO:0055114 oxidation-reduction process
GO:0006694 steroid biosynthetic process

Molecular Function

GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.