Family

Cytochrome c oxidase, subunit Vb (IPR002124)

Short name: Cyt_c_oxidase_su5b

Family relationships

None.

Description

Cytochrome c oxidase (EC:1.9.3.1) is an oligomeric enzymatic complex which is a component of the respiratory chain complex and is involved in the transfer of electrons from cytochrome c to oxygen [PMID: 6307356]. In eukaryotes this enzyme complex is located in the mitochondrial inner membrane; in aerobic prokaryotes it is found in the plasma membrane.

In eukaryotes, in addition to the three large subunits, I, II and III, that form the catalytic centre of the enzyme complex, there are a variable number of small polypeptidic subunits. One of these subunits, which is known as Vb in mammals, V in Dictyostelium discoideum (Slime mold) and IV in yeast, binds a zinc atom. The sequence of subunit Vb is well conserved and includes three conserved cysteines that coordinate the zinc ion [PMID: 1661610, PMID: 8638158]. Two of these cysteines are clustered in the C-terminal section of the subunit.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004129 cytochrome-c oxidase activity

Cellular Component

GO:0005740 mitochondrial envelope

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
GENE3D
PROSITE profiles
Pfam
PANTHER