DNA mismatch repair protein family (IPR002099)

Short name: DNA_mismatch_repair_fam

Overlapping homologous superfamilies


Family relationships


Mismatch repair contributes to the overall fidelity of DNA replication by targeting mispaired bases that arise through replication errors during homologous recombination and as a result of DNA damage. It involves the correction of mismatched base pairs that have been missed by the proofreading element of the DNA polymerase complex [PMID: 14527292]. This entry represents a family of evolutionarily related DNA mismatch repair proteins, including MutL, Mlh1 and 2, and Pms 1 and 2.

GO terms

Biological Process

GO:0006298 mismatch repair

Molecular Function

GO:0005524 ATP binding
GO:0030983 mismatched DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.