Scorpion long chain toxin/defensin (IPR002061)

Short name: Scorpion_toxinL/defensin

Overlapping homologous superfamilies

Family relationships


This family contains both neurotoxins and plant defensins. The mustard trypsin inhibitor, MTI-2, is a plant defensin. It is a potent inhibitor of trypsin with no activity towards chymotrypsin. MTI-2 is toxic for Lepidopteran insects, but has low activity against aphids [PMID: 12581313]. Brazzein is a plant defensin-like protein. It is pH-stable, heat-stable and intensely sweet protein [PMID: 10775411]. The scorpion toxin (a neurotoxin) binds to sodium channels and inhibits the activation mechanisms of the channels, thereby blocking neuronal transmission.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008200 ion channel inhibitor activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.