Family

Sodium/sulphate symporter (IPR001898)

Short name: Na/sul_symport

Family relationships

None.

Description

Integral membrane proteins that mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions (sodium symporters) can be grouped, on the basis of sequence and functional similarities into a number of distinct families. One of these families currently consists of the following proteins:

  • Mammalian sodium/sulphate cotransporter [PMID: 7690140].
  • Mammalian renal sodium/dicarboxylate cotransporter [PMID: 8967342], which transports succinate and citrate.
  • Mammalian intestinal sodium/dicarboxylate cotransporter.
  • Chlamydomonas reinhardtii putative sulphur deprivation response regulator SAC1 [PMID: 8641280].
  • Caenorhabditis elegans hypothetical proteins B0285.6, F31F6.6, K08E5.2 and R107.1.
  • Escherichia coli hypothetical protein yfbS.
  • Haemophilus influenzae hypothetical protein HI0608.
  • Synechocystis sp. (strain PCC 6803) hypothetical protein sll0640.
  • Methanocaldococcus jannaschii (Methanococcus jannaschii) hypothetical protein MJ0672.

These transporters are proteins of from 430 to 620 amino acids which are highly hydrophobic and which probably contain about 12 transmembrane regions.

GO terms

Biological Process

GO:0006814 sodium ion transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
PROSITE patterns
Pfam