Chromogranin A/B (IPR001819)

Short name: Chromogranin_AB

Overlapping homologous superfamilies


Family relationships


Chromogranins and secretogranins are acidic proteins present in the secretory granules of endocrine and neuro-endocrine cells [PMID: 2053134, PMID: 2684154]. Granins may be precursors of biologically-active peptides, or they may be helper proteins in the packaging of peptide hormones and neuropeptides - their precise role is unclear.

Chromogranins A and B are characterised by an N-terminal motif that includes 2 cysteine residues involved in disulphide bond formation.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0030141 secretory granule

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.