Transcription regulator HTH, Crp (IPR001808)

Short name: Tscrpt_reg_HTH_Crp

Domain relationships


Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. This family groups together a range of proteins, including anr, crp, clp, cysR, fixK, flp, fnr, fnrN, hlyX and ntcA [PMID: 14638413, PMID: 10550204]. Within this family, the HTH motif is situated towards the C terminus.

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003700 sequence-specific DNA binding transcription factor activity

Cellular Component

GO:0005622 intracellular

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.