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Overview
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Pathways & interactions
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Cross-references
Domain
NAD-dependent epimerase/dehydratase (IPR001509)
Short name: Epimerase_deHydtase
Overlapping homologous superfamilies
- NAD(P)-binding domain superfamily (IPR036291)
Domain relationships
- NAD(P)-binding domain (IPR016040)
- NAD-dependent epimerase/dehydratase (IPR001509)
Description
This domain is found in proteins that utilise NAD as a cofactor and use nucleotide-sugar substrates for a variety of chemical reactions [PMID: 9174344]. One of the best studied of these proteins is UDP-galactose 4-epimerase which catalyses the conversion of UDP-galactose to UDP-glucose during galactose metabolism [PMID: 11279032, PMID: 10801319].
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0003824 catalytic activity
GO:0050662 coenzyme binding
Cellular Component
No terms assigned in this category.
Contributing signatures
Signatures from InterPro member databases are used to construct an entry.
Pfam
- PF01370 (Epimerase)