Domain

NAD-dependent epimerase/dehydratase (IPR001509)

Short name: Epimerase_deHydtase

Domain relationships

None.

Description

This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions [PMID: 9174344]. It contains the NAD(P)- binding domain (IPR016040) which is a commonly found domain with a core Rossmann-type fold. One of the best studied of these proteins is UDP-galactose 4-epimerase which catalyses the conversion of UDP-galactose to UDP-glucose during galactose metabolism [PMID: 11279032, PMID: 10801319].

GO terms

Biological Process

GO:0044237 cellular metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0050662 coenzyme binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam