Family

ATP-binding cassette subfamily C member 9 (IPR001475)

Short name: ABCC9

Family relationships

Description

ATP-binding cassette subfamily C member 9 (ABCC9, also known as the sulphonylurea receptor SUR2) is an atypical member of the ABC transporter family. Although it has the requisite domains to function as a transporter, it is a regulator of a potassium channel to which it is directly coupled in a hetero-octameric complex [PMID: 23253866]. Mutations in ABCC9 cause Cantu syndrome (CS), a distinct multiorgan disease, potentially via enhanced KATP channel activity [PMID: 24700710].

GO terms

Biological Process

GO:0006813 potassium ion transport

Molecular Function

GO:0005524 ATP binding
GO:0008281 sulfonylurea receptor activity

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
PANTHER