Parathyroid hormone/parathyroid hormone-related protein (IPR001415)

Short name: PTH/PTH-rel

Overlapping homologous superfamilies


Family relationships


Parathyroid hormone (PTH) is a polypeptidic hormone that elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone-related protein (PTH-rP) is structurally related to PTH [PMID: 2682846] and seems to play a physiological role in lactation, possibly as a hormone for the mobilisation and/or transfer of calcium to the milk. It also regulates chondrocytic differentiation and endochondral bone formation [PMID: 11760831].

PTH and PTH-rP bind to the same G-protein coupled receptor.

This entry represents parathyroid hormone and parathyroid hormone-related protein.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005179 hormone activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns