Hydrophobin (IPR001338)

Short name: Hydrophobin

Overlapping homologous superfamilies


Family relationships



The surface of many fungal spores is covered by a hydrophobic sheath, the rodlet layer, whose main component is a protein known as the rodlet protein [PMID: 2065971, PMID: 1459459]. The rodlet proteins of Neurospora crassa (gene eas) and Emericella nidulans (gene rodA) are evolutionary related to proteins found in the cell wall of fruiting bodies of the mushroom Schizophyllum commune (Bracket fungus) [PMID: 2401401]. Collectively, these low-molecular-weight, cysteine-rich (eight conserved cysteines), hydrophobic proteins, are known as hydrophobins.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005199 structural constituent of cell wall

Cellular Component

GO:0009277 fungal-type cell wall

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.