Interleukin-4/interleukin-13 (IPR001325)

Short name: IL-4/IL-13

Overlapping homologous superfamilies

Family relationships


Interleukin-4 (IL-4) is a cytokine that plays a central role in the control and regulation of the immune and inflammatory system [PMID: 3284813, PMID: 1693082]. IL-4 is a participant in several B-cell activation processes. It also stimulates other cell types such as T cells or mast cells. IL-4 is a glycoprotein that contains three disulphide bonds [PMID: 1993171].

Interleukin-13 (IL-13) is a pleiotropic cytokine which may be important in the regulation of the inflammatory and immune responses [PMID: 8096327]. The sequences of IL-4 and IL-13 are distantly related. This entry represetns both IL-4 and IL-13.

GO terms

Biological Process

GO:0006955 immune response

Molecular Function

GO:0005126 cytokine receptor binding

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.