Domain

Class II aldolase/adducin N-terminal (IPR001303)

Short name: Aldolase_II/adducin_N

Domain relationships

None.

Description

This entry represents the alpha/beta/alpha domain found in class II aldolases and in adducin (usually at the N terminus of adducin). Proteins containing this domain include: rhamnulose-1-phosphate aldolase (EC:4.1.2.19), L-fuculose phosphate aldolase (EC:4.1.2.17) [PMID: 8515438, PMID: 8676381] that is involved in the third step in fucose metabolism, L-ribulose- 5-phosphate 4-epimerase (EC:5.1.3.4) involved in the third step of L-arabinose catabolism, a probable sugar isomerase SgbE and the metazoan adducins, which have not been ascribed any enzymatic function but which play a role in cell membrane cytoskeleton organisation [PMID: 1840603].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
SUPERFAMILY
Pfam
GENE3D