Domain

Phosphoinositide 3-kinase, accessory (PIK) domain (IPR001263)

Short name: PInositide-3_kin_accessory_dom

Domain relationships

  • Armadillo-type fold (IPR016024)
    • Phosphoinositide 3-kinase, accessory (PIK) domain (IPR001263)

Description

Phosphatidylinositol 3-kinase (PI3-kinase) (EC:2.7.1.137) is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. The role of the accessory domain of phosphoinositide 3-kinase (PI3-kinase) is unclear. It may be involved in substrate presentation [PMID: 8248783].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles
Pfam
SMART
GENE3D