Probable peptidoglycan glycosyltransferase FtsW/RodA (IPR001182)

Short name: FtsW/RodA

Overlapping homologous superfamilies


Family relationships


A number of prokaryotic integral membrane proteins involved in cell cycle processes have been found to be structurally related [PMID: 2509435, PMID: 2113157]. These proteins include, the Escherichia coli and related bacteria cell division protein ftsW and the rod shape-determining protein rodA (or mrdB), the Bacillus subtilis stage V sporulation protein E (spoVE), the B. subtilis hypothetical proteins ywcF and ylaO and the Cyanophora paradoxa cyanelle ftsW homologue. They constitute the SEDS (shape, elongation, division and sporulation) family. SEDS proteins are thought to be peptidoglycan polymerases, functioning as cell wall synthases of the cell elongation and division machinery [PMID: 27525505].

GO terms

Biological Process

GO:0051301 cell division

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.