Family

Interleukin-7 (IPR001181)

Short name: IL-7

Family relationships

Description

This entry represents interleukin-7 (IL7), it is a hematopoietic growth factor produced by bone marrow stromal cells. It promotes growth of B-cell precursors, and functions with IL2 in the activation of mature T-cells [PMID: 2643102, PMID: 3259677]. Interleukin-7 and Interleukin-9 belong to the same larger family.

GO terms

Biological Process

GO:0006955 immune response

Molecular Function

GO:0008083 growth factor activity
GO:0005139 interleukin-7 receptor binding

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
SMART
PIRSF