Domain

UvrC family homology region (IPR001162)

Short name: UvrC_homol_region

Domain relationships

None.

Description

In prokaryotes, nucleotide excision repair, DNA damage recognition and processing are achieved by the action of the uvrA, uvrB, and uvrC protein complex. UvrC proteins contain 4 conserved regions: the UVR domain which interacts with uvrB, a Helix hairpin Helix (HhH) domain important for 5 prime incision of damage DNA, the GIY-YIG domain and a central homology region of unknown function, which is specific for UvrC proteins.

This entry represents the homology region 2, which can be found between the Uvr domain and the C-terminal Helix-hairpin-Helix domain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PROSITE profiles