NADH-quinone oxidoreductase, subunit D (IPR001135)

Short name: NADH_Q_OxRdtase_suD

Overlapping homologous superfamilies

Domain relationships



This entry represents the subunit D (NuoD) of NADH-quinone oxidoreductase (EC: and the subunit H (NdhH) of NAD(P)H-quinone oxidoreductase ([intenz:1.6.5.-]). NADH-quinone (Q) oxidoreductase is a large and complex redox proton pump, which utilises the free energy derived from oxidation of NADH with lipophilic electron/proton carrier Q to translocate protons across the membrane to generate an electrochemical proton gradient [PMID: 11695831]. Subunit D (NuoD) is a 49kDa polypeptide that appears to be evolutionarily important in determining the physiological function of complex I/NDH-1 [PMID: 11695831].

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0051287 NAD binding
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0048038 quinone binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.