Domain

Translation elongation factor P/YeiP, central (IPR001059)

Short name: Transl_elong_P/YeiP_cen

Domain relationships

Description

Elongation factor P (EF-P) is a prokaryotic protein translation factor required for efficient peptide bond synthesis on 70S ribosomes from fMet-tRNAfMet [PMID: 9195040]. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

This entry reresents the central domain of elongation factor P and its homologues. It forms an oligonucleotide-binding (OB) fold, though it is not clear if this region is involved in binding nucleic acids [PMID: 15210970].

GO terms

Biological Process

GO:0006414 translational elongation

Molecular Function

GO:0003746 translation elongation factor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam