Acid phosphatase, class A, bacterial (IPR001011)

Short name: Acid_Pase_classA_bac

Overlapping homologous superfamilies

Family relationships



This group represents nonspecific acid phosphatases, class A [PMID: 8755883, PMID: 8081499]. Non-specific acid phosphatases are bacterial enzymes that catalyse the dephosphorylation of orthophosphoric monoesters to alcohol and phosphate, in addition to being able to catalyse transphosphorylation. As their name suggests, they show broad specificity, being able to phosphorylate a wide range of hydroxy compounds. During active catalysis, an activated phospho-enzyme intermediate is formed that is able to transfer its phosphate group to water, glucose or inosine. Nonspecific acid phosphatases share a conserved active site with mammalian glucose-6-phosphatases (G6Pase) [PMID: 12968332].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003993 acid phosphatase activity

Cellular Component

GO:0030288 outer membrane-bounded periplasmic space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.